It is metabolized intracellularly to the active moiety, lamivudine 5'-triphosphate.
Nucleosides other nucleosides other nucleosides that have recently become available include 3TC or Lamivudine and D4T or Stavudine.
Three drugs are licensed, as of 2004, for the treatment of chronic hepatitis B: Adefovir dipivoxil, alpha interferon, and lamivudine.
Dybul, M. et al. "A proof-of-concept study of short-cycle intermittent antiretroviral therapy with a once-daily regimen of didanosine, lamivudine, and efavirenz for the treatment of chronic HIV infection."
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