Hbf sentence example
- In thalassemia minor, fetal hemoglobin (HbF), the hemoglobin form that circulates in the fetus, does not decrease normally after birth and may remain high in later life.
- It also involves the persistence of HbF with larger than normal amounts appearing in the child's circulation.
- A fetal hemoglobin test (Hgb electrophoresis) measures the level of fetal hemoglobin (Hemoglobin F or HbF) in the blood of infants and children.
- Among the six types of hemoglobin, HbA is the normal adult hemoglobin, and HbF is the major fetal hemoglobin.
- For example, HbF can be found in higher levels in sickle cell anemia and other hereditary anemias.Advertisement
- When HbF is elevated after age four, the cause is typically investigated.
- Newborn to six months: HbF may be up to 70 percent of total hemoglobin.
- Six months to adult: HbF may be up to 2 percent of total hemoglobin.
- Sickle cell disease: Hemoglobin S 80-100%, Hgb A 0%, HbF 2%.
- Sickle cell trait: Hemoglobin S 20-40%, Hgb A 60-80%, HbF 2%.Advertisement
- Thalassemia major: HbF 65-100%, Hgb A 5-25%.
- Thalassemia minor: HbF 1-3%, Hgb A 50-90%.