Hbf sentence example

hbf
  • In thalassemia minor, fetal hemoglobin (HbF), the hemoglobin form that circulates in the fetus, does not decrease normally after birth and may remain high in later life.
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  • It also involves the persistence of HbF with larger than normal amounts appearing in the child's circulation.
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  • A fetal hemoglobin test (Hgb electrophoresis) measures the level of fetal hemoglobin (Hemoglobin F or HbF) in the blood of infants and children.
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  • Among the six types of hemoglobin, HbA is the normal adult hemoglobin, and HbF is the major fetal hemoglobin.
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  • For example, HbF can be found in higher levels in sickle cell anemia and other hereditary anemias.
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  • When HbF is elevated after age four, the cause is typically investigated.
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  • Newborn to six months: HbF may be up to 70 percent of total hemoglobin.
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  • Six months to adult: HbF may be up to 2 percent of total hemoglobin.
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  • Sickle cell disease: Hemoglobin S 80-100%, Hgb A 0%, HbF 2%.
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  • Sickle cell trait: Hemoglobin S 20-40%, Hgb A 60-80%, HbF 2%.
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  • Thalassemia major: HbF 65-100%, Hgb A 5-25%.
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  • Thalassemia minor: HbF 1-3%, Hgb A 50-90%.
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