By using urea, guanidine, thiourea and related compounds instead of amidines, one obtains the uracils.
CH(NH 2) ï¿½ Cooh, arginin or guanidine-a-amino-n-valerianic acid, (NH)(NH2)Cï¿½NHï¿½ (CH 2) 3 ï¿½CH(NH 2)ï¿½Cooh, ornithin or aa-diamino valerianic acid, ï¿½ (CH 2) 3 ï¿½ CH(NH 2) ï¿½ Coon, -(3-imidazol propionic acid, [[Hoocï¿½ Ch(Nh 2) ï¿½Ch 2 ï¿½ C: Chï¿½N:Chï¿½Nh]], proline or a-pyrrolidin carboxylic acid, [[Hoocï¿½ Ch.
When heated with ammonia it yields guanidine, and on boiling with alcoholic potash it yields potassium carbonate.
GUANIDINE, CN 3 H 5 or HN: C(NH 2) 2j the amidine of amidocarbonic acid.
Many derivatives of guanidine were obtained by J.
By the action of nitric acid on guanidine in the presence of sulphuric acid, nitroguanidine, HN: C(NH 2) NH NO 2 (a substance possessing acid properties) is obtained; from which, by reduction with zinc dust, amidoguanidine, HN :C(NH 2) NH NH 2, is formed.
By fusing guanidine with urea, dicyandiamidineH 2 N (HN): C NH CO NH 21 is formed.
Aniline combines directly with alkyl iodides to form secondary and tertiary amines; boiled with carbon disulphide it gives sulphocarbanilide (diphenyl thio-urea), CS(NHC 6 H 5) 2, which may be decomposed into phenyl mustard-oil, C 6 H 5 CNS, and triphenyl guanidine, C 6 H 5 N: C(NHC6H5)2.
When heated for some time with water to 140° C. in a sealed tube, it is transformed into ammonium thiocyanate, a similar result being obtained by heating the base alone for some hours to 160-170° C. On heating alone for some hours to r70-180° C. it is converted into guanidine thiocyanate.