The liver, spleen, haemolymph glands and other tissues.
Post mortem it is found in great abundance in the spleen and liver.
I and 2; (7) S.R.Christophers,"Reports on a parasite found in persons suffering from enlargement of the spleen in India," Sci.
The parasites are frequently more numerous in the spleen, bone-marrow, kidneys, &c., than elsewhere, and it has been found that multiplication goes on rather more actively in the capillaries of these organs.
Sleep may overtake the patient in the midst of the sweating stage, and he awakes, not without some feeling of what he has passed through, but on the whole well, with the temperature fallen almost or altogether to the normal, or it may be even below the normal; the pulse moderate and full; the spleen again of its ordinary size; the urine that is passed after the paroxysm deposits a thick brick-red sediment of urates.
The malarial cachexia that follows definite attacks of ague consists in a state of ill-defined suffering, associated with a sallow skin, enlarged spleen and liver, and sometimes.
In the interior organs there are indications of a compensating accumulation of blood, such as swelling of the spleen, engorgement (very rarely rupture) of the heart, with a feeling of oppression in the chest, and a copious flow of clear and watery urine from the congested kidneys.
The pancreas has two lobes or branches, a long one passing to the left and reaching the spleen, and a shorter right lobe.
- Of these the thyroid gland, the suprarenal bodies, the spleen, the bile, the bone marrow, the ovaries and some others have been investigated fully.
The bird's liver receives nearly all the blood from the stomach, gut, pancreas and spleen, as well as from the left liver itself, into the right hepatic lobe, by a right and left portal vein.
The spleen continues to enlarge; the urine is now scanty and high-coloured; the body temperature is high, but the highest temperatures occur during the chill; there is considerable thirst; and there is the usual intellectual unfitness, and it may be confusion, of the feverish state.
Melanine particles formed in the spleen in malaria, which pass along with the blood through the liver, are appropriated by the endothelial cells of the hepatic capillaries, and are found embedded within their substance.
The part of the spleen in the motley group of dyspepsias and anaemias, conspicuous as it often is, still remains very enigmatic.
In post-mortem examination, the most obvious pathological lesion is hypertrophy of the spleen, which may be very pronounced; the lymphatic glands in the neck, inguinal region, &c., are also often greatly swollen.
In the one case they are entirely restricted to the neighbourhood of the boil or ulcer, whereas in the other there is a general infection of the body, the organisms spreading to all parts and being met with in the spleen, liver, bone-marrow, &c., and (rarely) in the peripheral circulation.
Rogers," On the development of flagellated organisms (Trypanosomes) from the spleen Protozoic parasites of cachexial fevers and Kala-azar," Quart.
In some it is very marked, for example in some viscera, the spleen, the bladder, the ureter, the uterus, the intestine, and especially in the heart.
The spleen and liver are always enlarged, the former to sometimes twice or thrice its natural size.
It is also found in the thymus gland of calves and in the spleen of cattle.