Hydriodic acid at high temperature reduces pyrrol to pyrrolidine (tetra-hydropyrrol), C 4 H 8 NH.
As a useful preliminary it is convenient to divide heterocyclic ring systems into two leading groups: (I) systems resulting from simple internal dehydration (or similar condensations) of saturated aliphatic compounds - such compounds are: the internal anhydrides or cyclic ethers of the glycols and thioglycols (ethylene oxide, &c.); the cyclic alkyleneimides resulting from the splitting off of ammonia between the amino groups of diaminoparaffins (pyrrolidine, piperazine, &c.); the cyclic esters of oxycarboxylic acids (lactones, lactides); the internal anhydrides of aminocarboxylic acids (lactams, betaines); cyclic derivatives of dicarboxylic acids (anhydrides, imides, alkylen-esters, alkylenamides, &c.).
Pyrrolidine has also been prepared by A.
This substance easily splits out alcohol, and the ring compound then formed yields pyrrolidine on reduction by sodium in amyl alcohol solution.
An a-pyrrolidine carboxylic acid and its hydroxy derivatives have been detected by E.