Amongst other antipyretics, the most important are quinine, phenacetin and antifebrin.
Pain may be stopped by removing the cause of irritation, as, for example, by the extraction of a carious tooth or by rendering the nerveendings insensitive to irritation, as by the application of cocaine; by preventing its transmission along the spinal cord by antipyrin, phenacetin, acetanilide, cocaine, &c.; or by dulling the perceptive centre in the brain by means of opium or its alkaloids, by anaesthetics, and probably also, to a certain extent, by antipyrin and its congeners.
And antipyrin, phenacetin, aspirin and similar analgetics are commonly taken.
Phenacetin, acetanilide, phenazone and many similar bodies act as antipyretics in virtue of an action on the heat-regulating centres in the cerebrum.
Phenacetin, cold water, &c.