Sclerostomum armatum, y, X about 31, opened to show the phagocytic organs.
The body-cavity also contains the socalled phagocytic organs.
5, 6 and 7, Anterior middle and posterior pairs of phagocytic organs.
It was found that the tissues were attacked by phagocytic cells that became enlarged and carried away fragments of the tissue; the cells were subsequently identified as leucocytes or blood-cells.
This view is confirmed by the fate of the phagocytic cells.
Wright and others, in recent work on opsonins, have shown that, by injecting dead cultures of the causal agent into subjects infected with the organism, there is produced in the body fluids a substance (opsonin) which apparently in favourable conditions unites with the living causal bacteria and so sensitizes them that they are readily taken up and destroyed by the phagocytic cells of tissues.
Absorption of this infarcted zone is carried on by means of leucocytes and other phagocytic cells, and by new blood-vessels.
II.) - cells that are motile and extremely phagocytic to these bacteria.
If the abscess be deeply situated in some tissue and not able to open on to a free surface so allowing the contents to be drained off, the phagocytic cells play a very prominent part in the resolution of the abscess.
These phagocytic cells carry out the complete removal of all the injured warring elements and the damaged tissues of the part.
Note that these phagocytic cells are pushing out protoplasmic processes (pseudopodia) by which they grasp their victims. (X woo diam.) FIG.
But their disintegration is more commonly brought about by " phagocytosis " on the part of the phagocytic cells in the different organs concerned with the function of haemolysis, i.e.
- Phagocytic cells (in sputum) FIG.
The toxins produced by microbes, if too weak to destroy the leucocytes, induce them to secrete antitoxins, which not only act as antidotes to the toxins and are injurious to the microbes, but also increase the phagocytic power of the leucocytes (opsonius of Wright).
On the contrary the labile opsonins of normal serum have a comparatively general action on different organisms. It is quite evident that the specific immune-opsonins may play a very important part in the phenomena of immunity, as by their means the organisms are taken up more actively by the phagocytic cells, and thereafter may undergo rapid disintegration.
- One of the phagocytic organs of Sc. armatum, highly magnified.
These are amoeboid cells and are extremely phagocytic, their power of digestion being greatly developed.
Phagocytic reaction on the part of the organism against irritants.
The average number of bacteria contained within leucocytes in the case tested, divided by the number given by the normal serum, is called the phagocytic index.
From the shape and position of the phagocytic organs it is obvious that they form admirable strainers through which the fluid of the body-cavity filters (figs.