In the yeast cell the nucleus is represented by a homogenous granule, probably of a nucleolar nature, surrounded and perhaps to some extent impregnated by chromatin and closely connected with a vacuole which often has chromatin at its periphery, and contains one or more volutin granules which appear to consist of nucleic acid in combination with an unknown base.
" Nucleo-proteids," constituents of the cell-nucleus, are combinations of albumins and nucleic acid; they always contain iron.
Nucleic acid is at present of unknown constitution; decomposition products are: phosphoric acid, uracil or 2.6-dioxy-pyrimidin,1 cytosin or 2-oxy-6-amino-pyrimidin, thymin (nucleosin) or 2.6-dioxy-5-methyl pyrimidin hypoxanthin 1 or 6-oxypurin, xanthin or 2.6-dioxypurin, adenine or 6 amino-purin, guanine or 2amino-6-oxypurin, pentoses (l-xylose), laevulinic acid, ammonia, etc. The nucleic acids vary with the source of the proteids, there being considerable differences in chemical composition.
In the peritoneum, by injections of nonpathogenic organisms, peptone, nucleic acid and various other substances.