Pyruvic nitrile, or acetyl cyanide, CH 3 CO.
The half nitrile of malonic acid is cyanacetic acid, CN CH 2 COOH, which, in the form of its ester, may be obtained by the action of a solution of potassium cyanide on monochloracetic acid.
It melts at 70° C.and at higher temperatures decomposes, with evolution of carbon dioxide and formation of aceto-nitrile, CH 3 CN.
The true nitrile of malonic acid is methylene cyanide, CH 2 (CN) 2, which is obtained by distilling a mixture of cyanacetamide and phosphorus pentoxide.
This compound combines with hydrocyanic acid to form a nitrile which hydrolyses to dichlorhydroxy iso-butyric acid.
His earlier work included an investigation of succinic acid, and the preparation of phenyl cyanide (benzonitrile), the simplest nitrile of the aromatic series; but later his time was mainly occupied with questions of technology and public health rather than with pure chemistry.
Wohl forms the oxime and converts it into an acetylated nitrile by means of acetic anhydride and sodium acetate; ammoniacal silver nitrate solution removes hydrocyanic acid and the resulting acetate is hydrolysed by acting with ammonia to form an amide, which is finally decomposed with sulphuric acid.
CH 2 OH CH20H CH20H CH20H (CH OH) 3 -> 01 OH) 3 -> (CH OH) 3 --> (CH OH)3 CH OH CH OH CH OH CHO CHO CH:NOH CN Hexose -p Oxime -> Nitrile -> Pentose.
Its nitrile (prussic acid) has an acid character, a property not possessed by the nitriles of the other members of the series; and, by the abstraction of the elements of water from the acid,.
With urea it gives " /CH NN quinazolone I, and with mandelic nitrile and its H /C0 homologues it forms oxazole derivatives (S.
A-Naphthoic acid, C 1 oH 7 CO 2 H, is formed by hydrolysis of the nitrile, obtained by distilling potassiuma-naphthalene sulphonate with potassium cyanide (V.
It forms needles which melt at 160° C. (3-Naphthoic acid, obtained b y boiling 0-methylnaphthalene with dilute nitric acid, or by hydrolysis of its nitrile (formed when formyl-0-naphthalide is heated with zinc dust), crystallizes from alcohol in needles which Nitrosonaplithols or naphthoquinone-oxames, C 1 oH 6 (OH)(NO) or melt at 184° C. C 1 oH 6 (: NOH): 0.
It also unites directly with hydrocyanic acid to form the nitrile of a-oxyisobutyric acid.
Cyclo-propane carboxylic acid, C 3 H 5 CO 2 H, is prepared by heating the 1.1- dicarboxylic acid; and by the hydrolysis of its nitrile, formed by heating y-chlorbutyro-nitrile with potash (L.
The corresponding oxyacid is obtained by the hydrolysis of the nitrile, which is formed by the addition of hydrocyanic acid to suberone (A.
Water converts the former into ammonium thiophosphate, PO(SNH4)3.H20, whilst the latter heated to 300° in a vacuum gives thiophosphoric nitrile, NP:S (Stock, ibid., 1906, 39, p. 1967).