The most serious complication of AP is kidney inflammation (nephritis), which occurs in almost half of older affected children.
Allergic reactions to drugs are the most common cause of an inflammation of the kidneys called tubulointerstitial nephritis.
"Clinical Study on Treatment of Childhood Henoch-Schonlein Purpura Nephritis with Colquhounia Root Tablet."
If nephritis be present, it may be seriously aggravated, and the drug must therefore be withheld.
Widal, Lemierre and other French observers have noted a diminution in the excretion of chlorides in nephritis associated with oedema; Widal and Javal found that a chloride-free diet caused diminution in the oedema and a chloride containing diet an increase of oedema.
The acetate and the citrate are valuable mild diuretics in Bright's disease and in feverish conditions, and by increasing the amount of urine diminish the pathological fluids in pleuritic effusion, ascites, &c. In tubal nephritis they aid the excretion of fatty casts.
The following is a list of the principal conditions in which iodides are recognized to be of definite value: metallic poisonings, as by lead and mercury, asthma, aneurism, arteriosclerosis, angina pectoris, gout, goitre, syphilis, haemophilia, Bright's disease (nephritis) and bronchitis.