The British Pharmacopoeia contains (i) an extract of the fresh corm, having doses of 4 to i grain, and (2) the Vinum Colchici, made by treating the dried corm with sherry and given in doses of 10 to 30 minims. This latter is the preparation still most generally used, though the presence of veratrine both in the corm and the seeds renders the use of colchicine itself theoretically preferable.
They contain a volatile oil which does not occur in the corm, and their proportion of colchicine is higher, for which reason the Tinctura Colchici Seminum- dose 5 to 15 minims - is preferable to the wine prepared from the corm.
The pupils at Brienne, far from receiving a military education, were grounded in ordinary subjects, and in no very efficient manner, by brethren of the order, or society, of Minims. The moral tone of the school was low; and Napoleon afterwards spoke with contempt of the training of the "monks" and the manner of life of the scholars.
In order to reduce the pulse to its normal rate in these cases, without at the same time lessening the power of the heart, the drug must be given in doses of about two minims of the tincture every halfhour and then every hour until the pulse falls to the normal rate.
Ten to twenty minims of ether, subcutaneously injected, constitute perhaps the most rapid and powerful cardiac stimulant known, and are often employed for this purpose in cases of syncope under anaesthesia.
The dose for repeated administration is from 10 to 30 minims and for a single administration up to a drachm.
The volatile oil - oleum cubebae - is also official, and is the form in which this drug is most commonly used, the dose being 5 to 20 minims, which may be suspended in mucilage or given after meals in a cachet.
The oil may be given in capsules, or in the form of an emulsion, with or without maltextract, or success may be obtained by adding, to every two drachms of the oil, ten minims of pure ether and a drop of peppermint oil.
Dr., 60 minims to 1 minim.
The pharmacopoeial preparations of this acid are a 2% solution, which is given in doses of from two to six minims, the tinctura chloroformi et morphinae cornposita, which contains a half-minim of this solution in each ten minims, and the aqua laurocerasi, which owes its virtues to the presence of this acid, and is of inconstant strength, besides being superfluous.
A lotion containing ten minims of the dilute acid to an ounce of water and glycerin will relieve itching due to any cause; and is useful in some forms of neuralgia.
Of hydrochloride in i io minims. The United States pharmacopoeia also contains strychninae nitras and strychninae sulphas.
In dyspnoea due to emphysema, phthisis and asthma, strychnine is of service, given internally in doses of i to 3 minims of the liquor.
The pharmacopeial tincture may be given in doses of five to fifteen minims, and the infusion has the unusually small dose of two to four drachms - the dose of other infusions being an ounce or more.
At this time arose the Hieronymites founded in 1375, under the Augustinian rule, the Observants (1415) among the Franciscans (q.v.), and the Minims (founded c. 1460 by St Francis of Paola, q.v.), whose programme was to outdo the Minors or Franciscans.
In treating an actual and present attack of asthma, it is advisable to give the standardized tincture of belladonna - unless expense is no consideration, in which case atropine may itself be used - in doses of twenty minims every quarter of an hour as long as no evil effects appear.
In keloid 20 minims of a t o% solution is injected directly into the part.
In io minims; (4) Trochiscus Mor- phinae, gr.
The British Pharmacopeia contains a large number of preparations of cantharides, but the only one needing special mention is the tincture, which is meant for internal administration; the small dose is noteworthy, five minims being probably the maximum for safety.
In the latter disease 1 0 minims of the 2% solution has been given internally.
In persons who have a marked idiosyncrasy towards cinchonism, the symptoms may often be successfully averted if small doses of hydrobromic acid - io minims of the dilute solution - are given with the quinine.
Of the numerous preparations only two need be mentioned - the liquid extract (dose 10 minims to 2 drachms or more), and the hypodermic injection.
This oil is closely allied in composition to oil of turpentine and is given in doses of a half to three minims. The Spiritus juniperi of the British pharma copoeia is given in doses up to one drachm.