MAO inhibitors have largely been supplanted in therapy because of their high risk of significant side effects, most notably severe, possibly fatal high blood pressure, if foods or alcoholic beverages containing tyramine are consumed.
SSRIs should not be used with any drug that increases serotonin concentrations, including MAO inhibitors, tramadol, sibutramine, meperidine, sumatriptan, lithium, St. John's wort, ginkgo biloba, and some anti-psychotic agents.
When antidepressants are prescribed for episodes of bipolar depression, they are usually selective serotonin reuptake inhibitors (SSRIs) or, less often, monoamine oxidase inhibitors (MAO inhibitors).
Studies on MAO inhibitors have only been performed on adult patients, and there is as of 2004 no specific information comparing the use of MAO inhibitors in children with use in other age groups.
A rapid, potentially fatal increase in blood pressure can occur if foods or alcoholic beverages containing tyramine are ingested by a person already taking MAO inhibitors.
Monoamine oxidase (MAO) inhibitors-A type of antidepressant that works by blocking the action of a chemical substance known as monoamine oxidase in the nervous system.
From it issues the Kebbi (Mao Kebi) a tributary of the Benue, and through it flows a tributary of the Logone, the chief affluent of the Shari.
As they died, they shouted, 'Communist Party, Chairman Mao, save us.'
Yang also quotes Mao as saying in a 1959 meeting, When there is not enough to eat, people starve to death.
In 1966, Mao Zedong closed the universities in China and sent their students and professors to the country to farm.