The first screening test for SCID is a white blood cell count with a count of the lymphocytes (differential) because in most forms of SCID the lymphocyte count will be very low.
The virus affects a type of white blood cell called the B lymphocyte, producing characteristic atypical lymphocytes that may be useful in the diagnosis of the disease.
In this form of SCID the lymphocyte or white blood evaluation is identical to X-linked SCID but is autosomal recessive and, therefore, occurs in girls and boys.
If the numbers of all of these cell types are normal and SCID is still suspected, more specialized tests can be done to test the lymphocyte cell functions.
If the lymphocyte cell count is low, further testing is usually done to determine whether any particular type of lymphocyte is lower than normal.
Hyper-IgM syndrome is caused by mutations in a gene or genes in the body's T cells, which are a type of white blood cell or lymphocyte.
Vaccines may cause temporary suppression of delayed-type hypersensitivity skin reactions or alter certain lymphocyte function tests.
A type of B lymphocyte deficiency involves a group of disorders called selective immunoglobulin deficiency syndromes.
In some cases, no treatment is required for DiGeorge syndrome because T lymphocyte production improves on its own.
In some cases, no treatment is required for DiGeorge syndrome because T lymphocyte production improves.