It is invariably the result of some cause acting generally, such as renal disease, valvular defect of the heart, or an impoverished state of the blood; while a mere oedema is usually dependent upon some local obstruction to the return of blood or lymph, or of both, the presence of parasites within the tissue, such as the filaria sanguinis hominis or trichina spiralis, or the poisonous bites of insects.
While in the alimentary canal they are subjected to the action of the digestive fluids and the varied contents of the stomach and intestines, and after absorption they come under the influence of the constituents of the blood and lymph, and of the chemical action of the tissue cells.
His results, so far, have been confirmed by Starling, who finds that the amount of lymph-flow from the thoracic duct is dependent upon difference in pressure.
" Serumalbumin," or " blood-albumin," possibly C450H720N116S60140,, occurs in blood-serum, lymph, chyle, milk, &c.; its coagulation temperature is about 67°.
In all probability no excess of soluble lime salts in the blood or lymph can ever be deposited in healthy living tissues.
Form an insoluble calcium soap. The interaction between the soaps, the phosphates and the carbonates which are brought by the blood and lymph to the part results in the weaker fatty acids being replaced by phosphoric and carbonic acid, and thus in the formation of highly insoluble calcium phosphate and carbonate deposits in the disorganized tissues.
(x 75 diam.) pigment from the liver by the normal channels be prevented, as by obstruction of the main bile ducts, the bile will accumulate until it regurgitates or is absorbed into the lymph and blood vessels, and is carried in a soluble state throughout the tissues, thus producing a general staining - an essential characteristic of jaundice.
Heidenhain, on the other hand, rejected entirely the filtration view of lymph-formation, believing that the passage of lymph across the capillary wall is a true secretion brought about by the secretory function of the endothelial plates.
LazarusBarlow, again, looks upon the pouring out of lymph as evidence of the demands of the tissue-elements for nutrition.
It may be asked, however, whether a dropsical tissue is being held in a high state of nutrition, and whether, on the contrary, the presence of lymph in excess in its interstices does not tend to impair its vitality rather than to lend it support.
According to Rogowicz and Heidenhain, certain substances increase the quantity of lymph given off from a part by acting upon the cells of the capillary wall; they hold, in fact, that these substances are true lymphagogues.
In the dropsy of cardiac disease, owing to the deficient oxidation from stagnation of blood, metabolic products must accumulate in the tissues; also lymph return must be impeded by the increased pressure in the veins and so dropsy results (Wells).
Thus, while increased pressure in the blood or lymph vessels may be one factor, and increased permeability of the capillary endothelium another, increased osmotic pressure in the tissues and lymph is probably the most important in the production of dropsy.
309, also, " Question of Lymph Production," ibid.
163; Labbe, La Cytologic experimentale (Paris, 1898); Lazarus-Barlow, " Lymph Formation," Journ.
513; Starling, " Mechanical Factors in Lymph Production," Journ.
224, also a number of other papers bearing upon lymph-production, in same; Thorne, " Endothelia as Phagocytes," Arch.
The venom is generally introduced into the subcutaneous tissue, whence it reaches the general circulation by absorption through the lymph and blood-vessels.
The ventral side of the body in the atrial region is broad and convex, so that the body presents the appearance of a spherical triangle in transverse section, the apex being formed by the dorsal fin and the angles bordered by two hollow folds, the metapleural folds, each of which contains a continuous longitudinal lymph-space, the metapleural canal.
All living Echinoderms have a lacunar, haemal system of diverse origin; this, the ambulacral system, and the coelomic cavities, contain a fluid holding albumen in solution and carrying numerous amoebocytes, which are developed in special lymph-glands and are capable of wandering through all tissues.
Muller made numerous researches in various departments of physiology, and in particular he extended knowledge as to the mechanism of voice, speech and hearing, and as to the chemical and physical properties of lymph, chyle and blood.
In addition, the fluid constituents, such as the lymph and blood, may have their composition and bulk considerably altered, while the special senses, the temperature, and, in short, every function and tissue, may be more or less affected.
In another class of diseases, the organisms. first produce some well-marked local lesion, from which secondary extension takes place by the lymph or blood stream to other parts of the body, where corresponding lesions are formed.
It turns in part, but in part only, upon the laws regulating the effusion of lymph, and physiologists are by no means at one in their conclusions on this subject.
Thus Ludwig was of opinion that the lymph-flow is dependent upon two factors, first, difference in pressure of the blood in the capillaries and the liquid in the plasma spaces outside; and, secondly, chemical interchanges setting up osmotic currents through the vessel-walls.