Quite irrespective of the nature of the anatomical lesion, the finding of the diphtheria bacillus on the part affected and the inoculability of this upon a suitable fresh soil are the sole means by which the diagnosis can be made certain.
The common variety of bed-sore is the result of continuous pressure on and irritation of the skin, the vitality and resisting power of which are lowered by a lesion of the cord cutting off the trophic supply to the skin affected.
The acute bed-sore is, in some cases, a true trophic lesion occurring, as it may, on parts not subjected to continuous pressure or irritation.
Syphilitic lesion of the arteries, and likewise of other fibrous tissues, often involves grave consequential damage to nervous structures fed or supported by such parts.
In post-mortem examination, the most obvious pathological lesion is hypertrophy of the spleen, which may be very pronounced; the lymphatic glands in the neck, inguinal region, &c., are also often greatly swollen.
A post mortem examination was held, which showed not only grave derangement in the stomach and other organs, but a serious lesion of the brain.
Both these preparations should only be used in cases where it is possible to exclude any tuberculous foci, or by their action in breaking down protective fibrous tissues they may cause a quiescent lesion to become active.
The sensation of pain is felt in the brain, and the cause of it may be in the sensory centres of the brain alone, as in cases of hysterical pain, with no lesion to cause it.
In another class of diseases, the organisms. first produce some well-marked local lesion, from which secondary extension takes place by the lymph or blood stream to other parts of the body, where corresponding lesions are formed.
After death there is found one noteworthy lesion, a commencing acute inflammation of the internal ear.