The Immortal rubbed the injection spot with a grimace, stretched, and climbed inside the ring in the lowermost basement in the castle.
He found that the development of a gall is due to a temporary modification of the part affected, not, as is generally thought, in consequence of the deposition of an egg by the insect, but of the injection of a poisonous substance which has the effect of stimulating the protoplasm to develop a gall instead of normal structure.
Lubarsch succeeded in inducing it merely by the subcutaneous injection of turpentine, which produces its result, it is said, by exciting an abscess.
When the massecuite, well pugged and prepared for purging, is in the centrifugals, it is first washed with syrup of low density, to assist the separation of mother-liquor of similar quality, this washing being supplemented by the injection of pure syrup of high density, or " clairce," when very white sugar is required.
Suitable provision is made for the egress of syrup from the massecuite in the cells when undergoing purging in the centrifugal; and the washing of the crystals can be aided by the injection of refined syrup and completed by that of " clairce."
It can also be used with advantage in inoperable uterine cancer, favus and lupus, and as an injection in gonorrhoea and suppurative conditions of the ear.
In pain due to violent sciatica relief and even permanent cure has been obtained by the injection of morphine directly into the muscle of the affected part, and in the treatment of renal and hepatic colic morphine given subcutaneously will relieve the acute pain consequent on the passage of biliary and urinary calculi.
Morphine is recognized as one of the most useful drugs in the treatment of eclampsia, early injection often arresting the fits.
These disagreeable results, however, are not to be compared with the benefits obtained by the injection of anti-toxic serum, and this method of treatment is likely to maintain its place in therapeutics.
It was formerly supposed that the injection of attenuated cultures or dead organisms-vaccines in the widest sensewas only of service in producing immunity as a preventive measure against the corresponding organism, but the work of Sir Almroth Wright has shown that the use of such vaccines may be of service even after infection has occurred, especially when the resulting disease is localized.
The animal, after injection, must be kept in favourable surroundings, and any resulting symptoms noted.
Many of them, probably also of proteid nature, are much more resistant to heat; thus the intracellular toxins of the tubercle bacillus retain certain of their effects even after exposure to ioo° C. Like the extracellular toxins they may be of remarkable potency; for example, fever is produced in the human subject by the injection into the blood of an extremely minute quantity of dead typhoid bacilli.
Certain toxins resemble enzymes as regards their conditions of precipitation and relative instability, and the fact that in most cases a considerable period intervenes between the time of injection and the occurrence of symptoms has been adduced in support of the view that enzymes are present.
In short, if we place aside the outstanding exception of tumour growth, we may say that practically all the important phenomena met with in disease may be experimentally produced by the injection of bacteria or of their toxins.
A second method is by injection of the bacterium in the dead condition, whereby immunity against the living organism may be produced.
(b) Antitoxin acts more powerfully when injected along with the toxin than when injected at the same time in another part of the body; if its action were on the tissue-cells one would expect that the site of injection would be immaterial.
The effect of the injection of a small quantity of vaccine is usually to produce an increase in the opsonic index within a few days.
If the amounts of vaccine used and the times of the injection are suitably chosen, there may thus be produced by a series of steps a rise of the opsonic index to a high level.
A large space around the greatly developed callosities on the buttocks, as well as the upper part of the insides of the thighs, is naked and of a crimson colour, shading off on the sides to lilac or blue, which, depending upon injection of the superficial blood-vessels, varies in intensity according to the condition of the animal - increasing under excitement, fading during sickness, and disappearing after death.
Under the name of anti-opium cure various remedies containing morphine in the form of powder, or of little pills, have been introduced, as well as the subcutaneous injection of the alkaloid, so that the use of morphine is increasing in China to an alarming extent, and considerable difficulty is experienced in controlling the illicit traffic in it, especially that sent through the post.
Chronic opium poisoning by the taking of laudanum - as in the familiar case of De Quincey - need not be considered here, as the hypodermic injection of morphine has almost entirely supplanted it.
Salts of silver are most useful as an injection in subacute and chronic gonorrhoea, either the nitrate (I to 5% solution) being employed, or protargol, which is a proteid compound containing 8% of silver nitrate, is used in 1% solution; they also benefit in leucorrhoea.
The drug should regularly be given hypodermically, and it is important to note that if the injection be made immediately under the skin, an abscess, or considerable discomfort, may ensue.
The injection should be intra-muscular, the needle being boldly plunged into a muscular mass, such as that of the deltoid or the gluteal region.
They may be applied externally as fomentations, for the relief of tormina; by rectal injection for the relief of the tenesmus and irritability of the bowel; hypodermically in advanced cases, for the relief of the general distress.
This effect is the same however the drug be administered, as, even after subcutaneous injection, the arsenic is excreted into the stomach after absorption, and thus sets up gastritis in its passage through the mucous membrane.