Edward is saying the book is 'based on the life of Annie Quincy Martin' just so he can take some liberties with the inconsequential details that have been lost in time.
On the way, Dean chatted about inconsequential things but pointedly asked about school.
At the first drop of laser missiles, Brady had figured there was one thing that would make the fed jets target the inconsequential town, and it was Lana.
Maybe she hadn't thought of it because it seemed inconsequential at the time.
An inconsequential little voice said she should stop this because it was nothing more than lust on his part.