Vezhdovsky has lately seen reasons for regarding the blood system as originating entirely from the hypoblast by the secretion of fluid, the blood, from particular intestinal cells and the consequent formation of spaces through pressure, which become lined with these cells.
The hypoblast in some forms originates by invagination, in others by delamination.
That portion of the gut which is formed by the hypoblast, whereas in Hexapod insects the similar caecal tubes are developed from the proctodaeum or in -pushed portion of the gut which is formed from epiblast.
Moreover, the body cavity of the rotifers is a primitive archicoele; the persistent or accrescent cleft between epiblast and hypoblast, traversed by mesenchymal muscular bands.
The little mass of hypoblast or enteric cell-mass now enlarges, but remains connected with the cicatrix of the blastopore or orifice of invagination by a stalk, the rectal peduncle.
A, Cavity surrounding fin ray; a', fin ray; b, muscular tissue of myotome; c, nervecord; d, notochord; c, left aorta; f, thickened ridges of epithelium of praeoral chamber (Rader organ); g, coiled tube lying in a coelomic space on right side of praeoral hood, apparently an artery; h, cuticle of notochord; i, connective-tissue sheath of notochord; k, median ridge of skeletal canal of nerve-cord; 1, skeletal canal protecting nerve-cord; m, inter-segmental skeletal septum of myotome; n, subcutaneous skeletal connective tissue; o, ditto of metapleur (this should be relatively thicker than it is); q, subcutaneous connective tissue of ventral surface of atrial wall (not a canal, as supposed by Stieda and others); r, epiblastic epithelium; s, gonad-sac containing ova; t, pharyngeal bar in section, one of the "tongue" bars alternating with the main bars and devoid of pharyngo-pleural fold and coelom; v, atrio-coelomic funnel; w, socalled "dorsal" coelom; x, lymphatic space or canal of metapleur; y, sub-pharyngeal vascular trunk; z, blood-vessel (portal vein) on wall of hepatic caecum; aa, space of atrial or branchial chamber; bb, ventral groove of pharynx (anteriorly this takes the form of a ridge); cc, hyperbranchial groove of pharynx; dd, lumen or space of hepatic caecum; ee, narrow coelomic space surrounding hepatic caecum; $, lining cell-layer of hepatic caecum; gg, inner face of a pharyngeal bar clothed with hypoblast, the outer face covered with epiblast (represented black); hh, a main pharyngeal bar with projecting pharyngeal fold (on which the reference line rests) in section, showing coelomic space beneath the black epiblast; ii, transverse ventral muscle of epipleura; kk, raphe or plane of fusion of two down-grown epipleura; 11, space and nucleated cells on dorsal face of notochord; mm, similar space and cells on its ventral face.
The embryo now consists of two layers of cells, epiblast and hypoblast, surrounding a cavity, the archenteron, which opens to the exterior by the orifice of invagination or blastopore.
The hypoblast is formed either by a definite invagination or by the immigration of isolated cells, known as vitellophags, which wander through the yolk and later become associated into a definite mesenteron, or by some combination of these two methods.