Of the hydrochloride may stimulate the cardiac action.
Examples of the first case are found among the colourless acridines and quinoxalines which give coloured salts; of the second case we may notice the colourless hydrochloride and sulphate of the deep yellow o-aminobenzophenone.
HO N Aldoximes are generally obtained by the action of hydroxylamine hydrochloride on the aldehyde in presence of sodium carbonate; the oxime being then usually extracted from the solution by ether.
Soc., 18 9 8, 73, p. 35 2) as a colourless liquid by the addition of hydroxylamine hydrochloride to an aqueous solution of formaldehyde in the presence of sodium carbonate; the resulting solution was extracted with ether and the oxime hydrochloride precipitated by gaseous hydrochloric acid, the precipitate being then dissolved in water, the solution exactly neutralized and distilled.
Chloraloxime, CC1 3 CH: NOH, is obtained when one molecular proportion of chloral hydrate is warmed with four molecular proportions of hydroxylamine hydrochloride and a little water.
It crystallizes in prisms which melt at 39° C. A chloral hydroxylamine, CC1 3 [[Choh Nhoh]], melting at 98° C. is obtained by allowing a mixture of one molecular proportion of chloral hydrate with two molecular proportions of hydroxylamine hydrochloride and one of sodium carbonate to stand for some time in a desiccator.
Glyoxime, HON: CH CH: NOH, obtained from glyoxal and hydroxylamine, or by boiling amidothiazole with excess of hydroxylamine hydrochloride and water, melts at 178° C. and is readily soluble in hot water.
Succinic aldehyde dioxime, HON: CH CH2 CH2 CH: NOH, is obtained by boiling an alcoholic solution of pyrrol with hydroxylamine hydrochloride and anhydrous sodium carbonate (G.
The 0-form is obtained by the direct action of hydroxylamine hydrochloride on mesityl oxide, the hydrochloride so formed being decomposed by sodium carbonate.
It is a monacid base; the hydrochloride, C 20 H 17 N0 4 HC1, is insoluble in cold alcohol, ether and chloroform, and soluble in 500 parts of water; the acid sulphate, C 20 H 17 N0 4 H 2 SO 4, dissolves in about loo parts of water.
Trimethylamine, (CH3)3N, is very similar to dimethylamine, and condenses to a liquid which boils at 3.2-3.8° C. It is usually obtained from "vinasses," the residue obtained from the distillation of beet sugar alcohol, and is used in the manufacture of potassium bicarbonate by the Solvay process, since its hydrochloride is much more soluble than potassium carbonate.
At a temperature of about 300-400° C. the alkyl chloride formed in this reaction attacks the benzene nucleus and replaces hydrogen by an alkyl group or groups, forming primary amines homologous with the original amine; thus methylaniline hydrochloride is converted into paraand ortho-toluidine hydrochloride, and trimethyl phenyl ammonium iodide is converted into mesidine hydriodide.
The gold chloride of commerce, which is used in photography, is really a hydrochloride, chlorauric or aurichloric acid, HAuC1 4.3H 2 O, and is obtained in long yellow needles by crystallizing the acid solution.
They are readily reduced to the corresponding hydroquinones or para-dihydroxy-benzenes, and also combine with hydroxylamine hydrochloride to form nitrosophenols, ON C 6 H 4.
Reinders (Ber., 1896, 29, p. 1369), who found that the reaction is monomolecular, and that the velocity constant of the reaction is proportional to the amount of the hydrochloride of the base present and also to the temperature, but is independent of the concentration of the diazoamine.
When heated with aniline and aniline hydrochloride they yield indulines.
P. 670) that the velocity of formation of the amino-azo compound depends only on the nature of the reagents and not on the concentration, and that in coupling the hydrochloride of a tertiary amine with diazobenzene suiphonic acid the reaction takes place between the acid and the base set free by the hydrolytic dissociation of its salt, for the formation of the amino-azo compound, when carried out in the presence of different acids, takes place most rapidly with the weakest acid (H.
It may also be prepared by oxidizing benzyl alcohol with concentrated nitric acid; by distilling a mixture of calcium benzoate and calcium formate; by the condensation of chlor-oxalic ester with benzene in the presence of aluminium chloride, the ester of the ketonic acid formed being then hydrolysed and the resulting acid distilled: C 6 H 6 +Cl CO Cooc 2 H 5 = C,H5co COOC2H5d-HC1, C 6 H 5 CO 000H =C6H5CHO+C02; by the action of anhydrous hydrocyanic acid and hydrochloric acid on benzene, an aldime being formed as an intermediate product: C 6 H 6 +HCN+HC1= C6H5CH :NH HC1, Benzaldine hydrochloride C 6 H 5 CH: NH HC1+H 2 O =NH4C1+C6H5CHO; and by the action of chromium oxychloride on toluene dissolved in carbon bisulphide (A.
Of hydrochloride in i io minims. The United States pharmacopoeia also contains strychninae nitras and strychninae sulphas.
With nitrosodimethylaniline hydrochloride it forms Meldola's Blue (dimethylaminonaphthophenoxazonium chloride), C18H15N20C1 (R.
Two are known, namely 4-nitroso-a-naphthol or 13; a-naphthoquinone-oxime, formed by the action of nitrous acid on a-naphthol or of hydroxylamine hydrochloride on a-naphthoquinone (H.
Schmidt, Ber., 1884, 17 p. 2064); and 2-nitrouo-a-naphthol (, -naphthoquinone-oxime), formed by the action of hydroxylamine hydrochloride on 13-naphthoquinone.
The first aliphatic diazo compound to be isolated was diazoacetic ester, CH N2 CO 2 C 2 H 5 i which is prepared by the action of potassium nitrite on the ethyl ester of glycocoll hydrochloride,HCl NH2 CH2 C02C2H 5 -1-KNO 2 =CHN 2 CO 2 C 2 H 5+ KCI+2H 2 O.
Diazosuccinic ester, N2 C(C02C2H5)2, is similarly prepared by the action of nitrous acid on the hydrochloride of aspartic ester.
By the action of bleaching powder on methylamine hydrochloride, there is obtained a volatile liquid (methyldichloramine, CH 3 -N C1 2), boiling at 58-60° C., which explodes violently when heated with water, yielding hydrocyanic acid (CH 3 NC1 2 =HCN+2HC1).
Well-dried hydroxylamine hydrochloride is dissolved in methyl alcohol and mixed with sodium methylate; a solution of methyldichloramine in absolute ether is then added and an ethereal solution of diazomethane distils over.
Formamidine, HC: (NH)NH 2, is only known in the form of its salts, the hydrochloride being obtained by the action of ammonia on the hydrochloride of formimido-ethyl ether (A.
Its hydrochloride melts at 163° C., and crystallizes from alcohol in colourless deliquescent prisms. Acetic anhydride converts the base into an acetamino-dimethyl pyrimidine, acetic acid and acetamide being also formed.
Freund, Ber., 1895, 28, p. 94 6; 1896, 29, p. 2501), crystallizes in long needles, which melt at 181-183° C. The addition of sodium nitrite to an aqueous solution of its hydrochloride converts it into amido-triaz / N N sulphol S< 1.
The hydrochloride with potassium cyanate C(NH 2): N gives hydrazothio-carbonamide, NH2 C0 NH NH CS NH2.
Of the hydrochloride to the fl.
Aniline hydrochloride forms large colourless tables, which become greenish on exposure; it is the "aniline salt" of commerce.
Monomethyl and dimethyl aniline are colourless liquids prepared by heating aniline, aniline hydrochloride and methyl alcohol in an autoclave at 220°.
The residue is extracted by absolute alcohol, which dissolves the hydroxylamine hydrochloride and a little ammonium chloride; this last substance is removed as ammonium platinochloride, and the residual hydroxylamine hydrochloride is recrystallized.
Lobry de Bruyn from the hydrochloride, by dissolving it in absolute methyl alcohol and then adding sodium methylate.
Cyclo-heptanol, C,H 13 0H, is formed by the reduction of suberone, and by the action of silver nitrite on the hydrochloride of cyclo- hexanamine (N.
The hydrochloride of the latter base when distilled over zinc dust yields a-propyl pyridine.
The sulphate is still used in medicine, and the British Pharmacopeia has admitted two others, which are much more valuable - the hydrochloride and the acid hydrochloride - whilst the hydrobromide is also used.
The hydrochloride - formerly known as the hydrochlorateC20H24N202 HCl.
The acid hydrochloride is the most valuable of all salts of quinine.
The absorption of the acid hydrochloride is much more complete.
Quinine hydrochloride circulates in the alkaline blood without precipitation, probably owing to the presence of carbonic acid in the blood.