Healing by second intention, or granulation, is usually seen where there has been loss of tissue, or extensive damage.
At a period corresponding to the condensation of the fibrous laminae and the disappearance of the cellular character of the granulation tissue.
I iuroblasts in young temporary granulation tissue.
- Healing abscess showing a wall of young cellular and vascular granulation tissue, which separates the pus area (top of Fig.) from the muscle fibres seen at lower part of Fig.
These changes are found in senile wasting, in metaplasia of cartilage, in many tumours, especially mixed growths of the parotid gland and testicle, and in various inflammatory granulation ulcers.
This is accomplished by a twofold agency, for while numbers of them are seized upon by the granulation phagocytes, others are broken up and dissolved by the liquid filling the granulation interspaces (Afanassieff).
I.; Afanassieff, " Granulation Tissue and Infection," Centralbl.
By so doing a far greater weight of surplus per hive may be secured, and extracted honey will keep in good condition for years, while comb-honey must be sold before granulation sets in.
Acute inflammation of various types, suppuration, granulation-tissue formation, &c., represent some of the complex resulting processes.