In 2006, a pig was genetically engineered to produce healthy omega-3 fatty acids.
It splits it into a fatty acid and glycerine, but seems to have no further action.
The suberized and cuticularized cell-walls appear to contain a fatty body called suberin, and such cell-walls can be stained red by a solution of alcanin, the lignified and cellulose membranes remaining unstained.
It is obtainable from most natural fatty bodies by the action of alkalis and similar reagents, whereby the fats are decomposed, water being taken up, and glycerin being formed together with the alkaline salt of some particular acid (varying with the nature of the fat).
Owing to their possession of this common property, these natural fatty bodies and various artificial derivatives of glycerin, which behave in the same way when treated with alkalis, are known as glycerides.
It is noticeable that with few exceptions the fatty and oily matters occurring in nature are substances analogous to tristearin, i.e.
Some other glycerides isolated from natural sources are analogous in composition to tristearin, but with this difference, that the three radicals which replace hydrogen in glycerin are not all identical; thus kephalin, myelin and lecithin are glycerides in which two hydrogens are replaced by fatty acid radicals, and the third by a complex phosphoric acid derivative.
Palm oil, it exists in the free state, so that it can be separated by washing with boiling water, which dissolves the glycerin but not the fatty glycerides.
The rationale of this treatment is not fully understood, but the action appears to consist in the separation or decomposition of the aromatic hydrocarbons, fatty and other acids, phenols, tarry bodies, &c., which lower the quality of the oil, the sulphuric acid removing some, while the caustic soda takes out the remainder, and neutralizes the acid which has been left in the oil.
SOAP, a chemical compound or mixture of chemical compounds resulting from the interaction of fatty oils and fats with alkalis.
In a scientific definition the compounds of fatty acids with basic metallic oxides, lime, magnesia, lead oxide, &c., should also be included under soap; but, as these compounds are insoluble in water, while the very essence of a soap in its industrial relations is solubility, it is better to speak of the insoluble compounds as " plasters, " limiting the name " soap " as the compounds of fatty acids with soda and potash.
Geoffroy in 1741 pointed out that the fat or oil recovered from a soap solution by neutralization with a mineral acid differs from the original fatty substance by dissolving readily in alcohol, which is not the case with ordinary fats and oils.
These discoveries of Geoffroy and Scheele formed the basis of Chevreul's researches by which he established the constitution of oils and the true nature of soap. In the article Oils it is pointed out that all fatty oils and fats are mixtures of glycerides, that is, of bodies related to the alcohol glycerin C 3H5(OH)3 i and some fatty acid such as palmitic acid (C 16 H 31 0 2)H.
But in this case the fatty acid unites with the alkali into its potash or soda salt, forming a soap C3H5(C16H3102)3+3NaOH =3NaC16H3102+C,H5(OH) 3 Palmitin.
Of the natural fats or glycerides contained in oils the most important in addition to palmitin are stearin and olein, and these it may be sufficient to regard as the principal fatty bodies concerned in soapmaking.
Almost without exception potash soaps, even if made from the solid fatty acids, are " soft," and soda soaps, although made with fluid olein, are " hard "; but there are considerable variations according to the prevailing fatty acid in the compound.
As to the detergent action of a soap, Berzelius held that it was due to the free alkali liberated with water; but it is difficult to see why a solution which has just thrown off most of its fatty acids should be disposed to take up even a glyceride, and, moreover, on this theory, weak cold solutions, in which the hydrolysis is considerable, should be the best cleansers, whilst experience points to the use of hot concentrated solutions.
As regards processes of manufacture soaps may be made by the direct combination of fatty acids, separated from oils, with alkaline solutions.
In the manufacture of stearin for candles, &c., the fatty matter is decomposed, and the liquid olein, separated from the solid fatty acids, is employed as an ingredient in soapmaking.
All other soaps result from the combination' of fatty oils and fat with potash or soda solutions under conditions which favour saponification.
The processes of soap manufacture may be classified (a) according to the temperatures employed into (I) cold processes and (2) boiling processes, or (b) according to the nature of the starting material - acid or oil and fat - and the relative amount of alkali, into (1) direct saturation of the fatty acid with alkali, (2) treating the fat with a definite amount of alkali with no removal of unused lye, (3) treating the fat with an indefinite amount of alkali, also with no separation of unused lye, (4) treating the fat with an indefinite amount of alkali with separation of waste lye.
The process of manufacturing soaps by boiling fatty acids with caustic alkalis or sodium carbonate came into practice with the development of the manufacture of candles by saponifying fats, for it provided a means whereby the oleic acid, which is valueless for candle making, could be worked up. The combination is effected in open vats heated by a steam coil and provided with a stirring appliance; if soda ash be used it is necessary to guard against boiling over.
Lye still continues to be poured in till a sample tastes distinctly alkaline - a test which indicates that the whole of the fatty acids have been taken up by and combined with the alkali.
Yellow Soap consists of a mixture of any hard fatty soap with a variable proportion - up to 40% or more - of resin soap. That substance by itself has a tenacious gluey consistence, and its intermixture in excess renders the resulting compound soft and greasy.
The ordinary method of adding resin consists in stirring it in small fragments into the fatty soap in the stage of clear-boiling; but a better result is obtained by separately preparing a fatty soap and the resin soap, and combining the two in the pan after the underlye has been salted out and removed from the fatty soap. The compound then receives its strengthening boil, after which it is fitted by boiling with added water or weak lye, continuing the boil till by examination of a sample the proper consistency has been reached.
The more usual method is to take milling soap, neutralize it with sodium bicarbonate or a mixture of fatty acids, and, after perfuming, it is aerated by mixing the hot soap with air in a specially designed crutcher.
The most important points in soap analysis are (1) determination of the fatty matter, (2) of the total alkali, (3) of the substances insoluble in water, (4) of the water.
The first is carried out by saponifying the soap with acid in the heat when the fatty acids come to the surface.
With genuine soaps, however, it suffices to calculate the fatty acids as anhydrides and add to this the amount of alkalis, and estimate the water by difference.
The complete analysis involves an examination of the fatty matter, of the various forms in which the alkalis are present - free and combined glycerin, &c.
From similar investigations of valerianic acid he was led to conclude that fatty acids were oxygen compounds of the radicals hydrogen, methyl, ethyl, &c., combined with the double carbon equivalent C2.
If the demand be for the red cells owing to loss from haemorrhage or any of the anaemias, the fatty marrow is rapidly replaced by cellular elements; this is mainly an active proliferation of the nucleated red cells, and gives rise to the erythroblastic type of marrow.
If the white cells be required, as in local suppurating abscess, general septicaemia, acute pneumonia, &c., there is an active proliferation of the myelocytes to form the polymorpho-nuclear leucocytes, so that we have in this condition a leucoblastic transformation of the fatty marrow.
The muscles suffer at an early period: they fall off in bulk, and later suffer from fatty degeneration, the heart being probably the first muscle to give way.
The fatty matter, however, it must be borne in mind, is the expression of dissimilation of the actual substance of the proteids of the tissues, not of the splitting up of proteids or other carbonaceous nourishment supplied to them.
When a nerve-trunk is separated from its central connexion, the distal portion falls into a state of fatty degeneration (Wallerian or secondary degeneration).
Thus workers in lead suffer from the effects of this substance as a poison, those who work in phosphorus are liable to necrosis of bone and fatty degeneration of the blood vessels and organs, and the many occupations in which dust is inhaled (coalmining, stone-dressing, steel-polishing, &c.; fig.
- Fatty degeneration of heart from case of perni cious anaemia.
- Fatty degeneration of kidney from case of starvation.
Fatty accumulations in the tissues of the body are found in health and in pathological conditions; these are usually recognized and described as fatty infiltrations and fatty degenerations, but there are intermediate conditions which make it difficult to separate sharply these processes.
In acute and chronic alcoholism, in phthisis, and in other diseases this fatty condition may be very extreme, and is commonly found in association with other tissue changes, so that probably we should look on these changes as a degeneration.
Fatty degeneration is a retrogressive change associated with the deposit of fatty granules or globules in the cytoplasm, and is caused by disorganized cellular activity (figs.