The plague of 1665, carried hither from London, almost depopulated this village, and the name of the rector, William Mompesson, attracted wide notice on account of his brave attempts to combat the outbreak.
In the 18th century it is said to have contained 20,000 inhabitants, but it was almost depopulated by plague in 1814.
It changed hands more than once in the wars between Pisa and Genoa in the 12th and 13th centuries; from 1390 it belonged to the prince of Piombino, but was depopulated in 1553 by the Turkish fleet, and only resettled at the beginning of the 19th century.
Pure-blooded Indians are not numerous, as whole districts were depopulated and whole tribes exterminated by the Spanish colonists and the buccaneers.
In Italy there was a great mortality in 543, but the most notable epidemic was in 565, which so depopulated the country as to leave it an easy prey to the Lombards.
Although Palestine had not been depopulated, and many of the exiled Jews remained in Persia, the standpoint is that of those who returned from Babylon.
Thenceforward its position was dependent, and in the Second Punic War, after several vicissitudes, it was depopulated and plundered by Hannibal.
Into these depopulated areas there was also a considerable immigration of Basuto, Bechuana and other Bantu tribes.
During the Turkish occupation the district was nearly depopulated, and allowed to lie almost desolate in marsh and heath and forest.
Italy was recovered for the empire, but it was an Italy terribly impoverished and depopulated, whose possession carried little strength with it.
Simultaneously with a terrible pestilence which is reported to have nearly depopulated China, plague prevailed over Germany, Holland, Italy and Spain, in the first decade of the century, and revived at various times in the first half.
As in the 16th century immense quantities of bullion were imported by the treasury, and were lavished upon war, luxury and the Church, while agriculture and manufactures continued to decline, and the countryside was depopulated by emigration to Brazil.
The country depopulated as the result of this delusion was afterwards peopled by European settlers, among whom were members of the German legion which had served with the British army in the Crimea, and some 2000 industrious North German emigrants, who proved a valuable acquisition to the colony.
The island of Santo Domingo was one of several in the West Indies which had early in the 16th century been almost depopulated by the oppressive colonial policy of Spain.
The egoism of the upper classes held military duty in contempt, while their avarice depopulated the countryside, whence the legions had drawn their recruits.
Alphonso swept all through that region, already more than half depopulated, slaying the lingering remnants of the Berbers, and carrying back the surviving Christians to the north.
Slave-raiding was practised on a scale which devastated and almost depopulated vast regions and greatly hampered the commercial activity of the large cities, of which Zaria and Kano were the most important.