Much motor weakness and cutaneous sensations similar to those above described soon follow.
Large doses also depress the nervous system, weakening the anterior horns of grey matter in the spinal cord so as ultimately to cause complete paralysis, and also causing a partial insensibility of the cutaneous nerves of touch and pain.
The first is flaccid and sluggish in its movements, and has not much power of contraction; its epipodial lobes are enormously developed and extend far forward along the body; it gives out when handled an abundance of purple liquid, which is derived from cutaneous glands situated on the under side of the free edge of the mantle.
And with certain cutaneous diseases accompanied by constitutional disturbances which afflict cattle, the affection in the skin appears on the patches bearing white hairs, the other parts remaining apparently healthy.
Not a hundredth part of the cerebellum has remained, and yet there has existed ability to stand, to walk, to handle and lift objects in a fairly normal way, without any trace of impairment of cutaneous or muscular sensitivity.
The initial indications of the disease were cutaneous itching, tingling and formication, which gave place to actual loss of cutaneous sensation, first observed in the extremities.
But sooner or later peripheral neuritis develops, usually beginning with sensory disturbances, tingling, numbness, formication and occasionally cutaneous anaesthesia.
When in a state of repose it is retracted, by a muscle arising from the sacrum, within the prepuce, a cutaneous fold attached below the symphysis pubis.
Many other substances, such as chrysarobin, mustard, pepper, &c., are also capable of irritating the skin, the effect produced varying from mere dilatation of the cutaneous vessels to destruction of tissue.
Following on a decided lowering of the pain and touch senses, which may even lead to complete loss of cutaneous sensation, there comes a sleep which is often accompanied by pleasant dreams. There appears to be no evidence in the case of either the lower animals or the human subject that the drug is an aphrodisiac. Excessive indulgence in cannabis indica is very rare, but may lead to general ill-health and occasionally to insanity.
We have here the interesting fact that a muscle (portion of the triceps humeri of the reptiles) has been reduced to a tendon, which in a secondary way has become connected with cutaneous muscles, which, when strongly developed, represent its belly.
On the under side of the free edge of the mantle are situated the numerous small cutaneous glands which, in the large A plysia camelus (not in other species), form the purple secretion which was known to s the ancients.
Petroleum has very long been known as a source of light and heat, while the use of crude oil for the treatment of wounds and cutaneous affections, and as a lubricant, was even more general and led to the raw material being an article of commerce at a still earlier date.
In Carinella, Cephalothrix, Polia and the Metanemertines the two tegumentary layers with their different glandular elements are fused into one; a thick layer of connective tissue is situated beneath them (instead of between them) and keeps the entire cutaneous system more definitely separate from the muscular (fi g s.
The first phalanges are expanded at their lower ends, and the wide, depressed middle phalanges embedded in a broad cutaneous pad, forming the sole of the foot, on which the animal rests in walking instead of on the hoofs.
Here, alone, at the distal portion of the tendon, occur muscular fibres, but these are unstriped, belonging to the category of cutaneous muscles.
Thus it is liable to cause a cutaneous erythema in the course of its excretion by the skin; it has a marked diuretic action; and it is a fairly efficient disinfectant of the urinary passages.
With the approach of night their season of activity commences, when they may be occasionally seen gliding from tree to tree supported on their cutaneous parachute, and they have been noticed as capable of traversing in this way a space of 70 yds.
He proposes to support the strength by placing the patient in a tepid bath of nutritious liquids, that might enter by cutaneous imbibition, but does not recommend this.
The skin is devoid of ossifications, but large and numerous cutaneous spines are often present, especially on the head and on the tail.