The chromatin is practically identical with nuclein.
If, from whatever cause, any of the chromatin loops belonging to the functional order be lost the descendants of such a cell, being unable to restore these loops, will be minus the functional attributes associated with the lost elements.
He thinks it may possibly originate in the vacuolization of the central region, and the accumulation of chromatin granules therein.
The Structure of the Nucleus.In the living condition the resting nucleus appears to consist of a homogeneous ground substance containing a large number of small chromatin granules and one or more large spherical granulesnucleolithe whole being surrounded by a limiting membrane which separates it from the cytoplasm.
The central body seems to consist merely of a spongy mass of slightly stainable substance, more or less impregnated with chromatin, which divides by constriction.
The chromatin is distributed throughout the cytoplasm in the form of granules which may be regarded as a distributed nucleus corresponding to what Hertwig has designated, in protozoa, chromidia.
The only evidence we have in pathology of living structures in which apparently a differentiation into cell-body and nucleus does not exist, is in the case of bacteria, but then there comes the question whether they may not possess chromatin distributed through their substance, in the form of metachromatic points, as is the case in some infusoria (Trachelocerca, Gruber).
Oertel finds an explanation of this want of complete celldifferentiation, loss of function, and acquired vegetative activity in the non-homogeneous character of the nuclear chromatin elements of the cell, and maintains that the different properties of the cell are carried and handed down by the different orders of chromatin loops.
Attention has accordingly been directed to the deeply-staining granules mentioned above, and the term chromatin-granules has been applied to them, and they have been considered to represent a rudimentary nucleus.
That these granules consist of a material similar to the chromatin of the nucleus of higher forms is very doubtful, and the comparison with the nucleus of more highly organized cells rests on a very slender basis.
It is clear, however, that an equal quantitative division and distribution of the chromatin to the daughter cells is brought about; and if, as has been suggested, the chromatin consists of minute particles or units which are the carriers of the hereditary characteristics, the nuclear division also probably results in the equal division and distribution of one half of each of these units to each daughter cell.
As they pass into this position they undergo a longitudinal splitting by which the chromatin in each chromosome becomes divided into equal halves.
Oertel thinks that in man we have these two different functions carried on by the one nucleus containing both chromatin orders.