In his medical work he belonged to the "methodical" school (see Asclepiades), as a philosopher, he is the greatest of the later Greek Sceptics.
At Megara he formed a life-long friendship with Asclepiades, with whom he toiled in the night that he might study philosophy by day.
The most eminent of these earlier Greek physicians at Rome was Asclepiades, the friend of Cicero (born 124 B.C. at Prusa in Bithynia).
He introduced a system which, so far as we know, was his own, though founded upon the Epicurean philosophical creed; on the practical side it conformed pretty closely to the Stoic rule of life, thus adapting itself to the leanings of the better stamp of Romans in the later times of the republic. According to Asclepiades all diseases depended upon alterations in the size, number, arrangement or movement of the "atoms," of which, according to the doctrine of Epicurus, the body consisted.
In the treatment of disease Asclepiades attached most importance to diet, exercise, passive movements or frictions, and the external use of cold water - in short, to a modified athletic training.
Asclepiades had many pupils who adhered more or less closely to his doctrines, but it was especially one of them, Themison, who gave permanence to the teachings of his master by framing out of them, with some modifications, a new system of medical doctrine, and founding on this basis a school which lasted for some centuries in successful rivalry with the Hippocratic tradition, which, as we have seen, was up to that time the prevailing influence in medicine.
Among his followers were Menedemus and Asclepiades, the leaders of the Eretrian school of philosophy.
40) with Asclepiades the Samian, and Lycidas, " the goatherd, of Cydonia," may well be the poet Astacides, whom Callimachus calls "the Cretan, the goatherd."