When a solution of the strength of about i in zo is applied to the skin it produces a local anaesthesia which lasts for many hours.
The subsequent experiments of Snellen, Senftleben, and, more lately, of Turner, seem to show that if the eyeball be protected from the impingement of foreign particles, an accident to which it is liable owing to its state of anaesthesia, the ulceration may be warded off indefinitely.
Bartlett, of Dr Horace Wells (1815-1848), the discoverer of anaesthesia; and one, by E.
Proposals have been made to employ hypnotism as a method of producing anaesthesia for surgical purposes, but there are two grave objections to such employment.
The fourth ocular result of administering atropine is the production of a slight but definite degree of local anaesthesia of the eyeball.
Morphine-scopolamine anaesthesia was introduced in 1902 by Steinbiickel.
It has been used by some surgeons for the production of anaesthesia previous to the administration of ether or chloroform, but the use of the method is now more usually relegated to obstetric practice.
It is largely used in dentistry and slight surgical operations to produce local anaesthesia, and is known by the trade-name kelene.
Its use as a local anaesthetic (see Anaesthesia) makes it the most valuable of the coca alkaloids, and it is much used in ophthalmic practice.
Applied to the conjunctiva it causes anaesthesia, dilatation of the pupil, diminution of the intraocular tension, and some interference with accommodation.
Thus there may be hyperaesthesia, anaesthesia, paralysis, or alterations of nutrition, such as wasting of muscles, whitening of the hair, &c.